The Health Extension Foundation and Entrepreneur’s Longevity Club Present:
Prof. Simon Melov
How can we screen for anti-aging compounds? What is the best way to create a therapy from there?
Come listen to Prof. Simon Melov from The Buck share his research on screening anti-aging compounds that have worked well in flies or worms, and find out how well they are doing in mammals, namely, mice.
Simon Melov is one of the founding faculty of the Institute, and has been at the Buck since its doors opened in 1999. He has broad expertise in multiple domains and model systems of aging, including C. elegans biology, functional decline with age in mice, the role of endogenous oxidative stress in the mitochondria, exercise physiology and age-related disease.
Over the last few years, a key focus of the Melov lab has been to define what “aging” means in the context of different organ systems in aging mice, and to use non-invasive techniques to quantitate and enumerate such functional changes. The end goal is to be able to relate age-related functional decline in mice to human aging. Other research interests include the development of molecular techniques to better understand how single cells change with age, and then to use that understanding to elucidate how such changes impact tissue function. See more about the lab here.